Pioneering Florida M.D. Reveals…
Why Bill Gates Wasted Over $400 Million Dollars on This Replacement for Probiotics
The Self-Made Billionaire Says the Key to Fighting Disease Is Hidden Inside Your Gut… But I’ll Tell You Exactly Where It Is Today
Most people know Bill Gates changed the world. 

It’s no accident he became the world’s richest man at a young age.  

Now, Gates is on a path to change the world of natural health. 

At a recent conference in Beijing, he told thousands of assembled people the future of medicine is going to target the human gut. 

And to make his point…

He brought a jar of poop on stage with him.

Gates explained how restoring our guts could hold the key to unlocking our bodies’ true potential… 
Bill Gates holds up a beaker of human feces at an expo in Beijing on November 6, 2018. 
Photo courtesy of Bill and Melinda Gates Foundation
That’s why his foundation is investing millions of dollars to create new gut-microbe therapies that could restore health on a global scale.

Gates hope is new probiotics — far more complex and microbe-rich than yogurt or fermented food — will help the world’s population reach a new level of health…

But… the truth is…
Bill Gates is getting it DEAD WRONG.
We don’t need to be introducing newer, more complex probiotics…

We need to be RE-introducing our lost probiotics.

The kind that kept our ancestors in peak health for hundreds of thousands of years.

How do I know?

Because that’s exactly what I’ve been doing to the hundreds of patients who’ve come through my doors.
And the results speak for themselves…
“I walk 2.2 km once or twice a day. I never thought I could feel this good again. Thank you.”
– Dan B., Thailand

“I feel great. I can sleep at night. I’m no longer bloated or irritable. I no longer take [the other products] I used to.” 
– Francine C.

“I feel better than I have ever felt in my life and I am 61.” 
– Valerie K., Canada
  • No more crippling costs
  • No more staying at home waiting for results
  • No more nauseating side effects
  • ​Or increased sensitivity
My patients are hitting the fairways…

And making dates with new friends and old. 
The Simple Gut Fix That Costs You Nothing
My patients understand what’s causing their discomfort… 

And they’re using a simple fix to maintain the ideal conditions within their gut.

It’s something you can do at home without spending a single cent.

And it’s the same solution Bill Gates is spending millions of dollars looking for…
One that will let him… 
  • Travel the world in comfort
  • Meet new people everyday
  • And live a carefree and happy life
Today, I’m going to share that solution with you.

And give you back the freedom to do what you want, when you want. But first, allow me to introduce myself… 

My name is Al Sears, MD.

I’m not what you’d call your typical doctor.

I don’t sit behind my desk doling out prescriptions all day…

Or send patients away on referrals. I’m a fixer. A doer.

I want my patients to feel strong and be happy…

Not walk through my doors every two weeks with the same problem. That’s why over the past 30 years…
I’ve traveled over 60,000 miles, covering 30 countries across six continents… 

Researching and developing new treatments and cures.

I’ve worked with leading institutes and clinics all around the world… Sharing my ideas and practices to advance medical knowledge. But my greatest discoveries aren’t made inside labs or hospitals…

They’re made in the wild…  Among the people who still live like our distant ancestors. People like the Hadza. 
A hunter-gatherer tribe from northern Tanzania.
Their Guts Are Three Times Healthier
Than Anyone Else’s
The Hadza have lived apart from mainstream society for thousands of years...  Preserving a way of life long forgotten here in the west.

Their basic existence seems primitive to most people… 

And yet according to researchers from Stanford, King’s College London, and Duke University… 
They have the healthiest guts on the planet.  The Hadza aren’t affected by digestive imbalances…

And… unlike most Americans...

They maintain fantastic health even into their old age. Their elders run alongside them, firm and fully capable of keeping up...

Even leading the hunts. So how do they do it? 

What gives the Hadza limitless strength and energy?
How do they stay clear of imbalances in their bowels and digestive tracts.? 

Well, despite leading their basic existence… The Hadza enjoy a better standard of diet than anyone else in the world. 
Location and scenery of Hadza land in Tanzania, Africa
In deep bush camps, hunting and gathering still provides over 90% of all food. (a) Location of Hadza land in northern Tanzania; (b) top of a rock ridge near Sengele camp overlooking a lush landscape in between two phases of the rainy season; (c) extent of the land surrounding Lake Eyasi where Hadza make their camp sites, orange border denotes land area in 1950s and area in yellow shows the reduced area Hadza occupy today; (d) view of baobab trees within Hadza land during the early dry season. 
The Million-Year-Old Diet
You see, the Hadza don’t grow their food…

They aren’t raising any livestock… 

They’re living a hunter-gatherer existence that hasn’t changed in 10,000 years. 

Their diet consists of food they find in the forest: 
  • Wild berries 
  • Fiber-rich tubers 
  • Honey
  • And wild meat. 
Members of the Hadza, a hunter-gatherer tribe in Tanzania.
Photo courtesy of Jeff Leach.
They eat no processed food — or even food that comes from farms.  Their reliance on nature’s bounty has made them naturally strong.

In fact, researchers at Stanford found the Hadza have one of the most resilient immune systems on the planet… [1]

Which is no coincidence given your gut is the cornerstone of your immune system.  Watching how the Hadza live taught me more than any textbook ever could.

It confirmed my long-held beliefs that modern medicine has got it all wrong when it comes to treating and preventing chronic disease.

Especially when dealing with the gut.  You see, many doctors write off common complaints as signs of ageing…

So instead of trying to cure you…  They’ll prescribe medications to relieve the symptoms.

But I can tell you now…

These so-called “everyday problems” are due to an underlying imbalances that need addressing.  And taking synthetic aids for the rest of your life is not the answer.

Here’s what I mean…
Your Gut Feeling Was Right All Along
You know that feeling you get in your gut when you know something’s up? The one most people are quick to dismiss…

It’s actually a series of chemical messages being sent directly to your brain.  Messages that warn the status quo has been upset.

Because while your brain is processing the information from the outside world…

Your gut is doing the same for the inside of your body.  Now, it’s no big surprise your gut and brain are in communication.

After all, 80% of your immune tissue sits in your gut. [2]

What is striking though…
Your GM is in constant communication with your brain, relaying messages about your internal health
Is how one-sided this conversation is. Ninety percent of gut-brain communication comes from your gut. [3]

Which means your brain is constantly listening to what your gut is telling it.

These messages come from your “GM.” Short for Gastrointestinal Microbiome or Gut Microbiome. 

Your GM is like your own unique microscopic world…

Made up of the trillions of bacteria and microorganisms living inside your colon. Together they’re known as “microbes” and significantly outnumber the cells in your body.

These microbes affect your metabolism and behavior in many different ways. [4]
They digest your food… 

Instruct your immune system… 

Protect your intestines from infections… 

Remove environmental toxins from the body…

And produce B vitamins and vitamin K. [5]

They even affect your mood…

Helping produce more than 90% of your body’s serotonin — the happy chemical. 

When there’s a problem with your GM…

You start experiencing the classic symptoms of an upset stomach: 
  • Trouble going to the bathroom 
  • Cramps
  • Incontinence
  • Diarrhea
And if left unchecked, any of these can turn into a serious problem.
A Perfect Gut in 3 Days
Now, remember when I said the Hadza have one of the most resilient immune systems on the planet…

And experience superior gut health in comparison to us here in the U.S.?

Well, scientists at the Max Planck Institute in Germany recently linked their ideal guts to the quality of their GMs.

You see, the Hadza were found to have the most diverse GM of anyone on the planet… 

In some cases, 130% diversity compared to your average westerner’s. [6]

This higher level of gut micro-diversity gives the Hadza a much greater ability to digest and extract nutrients from fiber-rich foods, Providing them with a cast-iron defense against a range of gut imbalances. 

Now, imagine if you could grow your gut to be as strong as the Hadza’s…

You could forget about those nagging problems… 

Stop regimenting your days And start living life to the fullest. Well… 

On a recent field trip to observe the Hadza way of life… 

A professor from King’s College London proved it can be done. He ate, slept and lived as one of the tribe for just three days… 

And in that time his gut diversity increased by a staggering 20%!  [7]

Proving beyond a shadow of a doubt… 

ANYONE can grow their gut’s defenses given the right conditions. 

All you need to do is maintain your gut’s natural diversity.  And the best part… 

You needn’t go and live like a tribesman in Africa… 

You can achieve the same results from your own home. 
Become a Master of Your Own Digestion
When Bill Gates discovered growing your GM’s diversity was key to maintaining good health even into your golden years…
He tasked his foundation with working with medical professionals like me to develop brand new gut technology.

Bill saw firsthand the more diverse your GM is:
  • The better your health…
  • The more resilient to imbalances you are…
  • And the better your standard of life.
In fact, a recent study by doctors at Johns Hopkins found increasing gut diversity reduced gut imbalances by 95%. [8]

And patients at the Tübingen University Medical Hospital in Germany…

Recovered 4x faster when their GM was boosted. [9]

Researchers at the University of Manchester, England took this one step further…

They enhanced the GM of 362 patients suffering from a range of different imbalances…
And reported successes across the board:
  • A reduction in discomfort caused by minor digestive imbalances. 
  • Improved body function. 
  • Clearer skin. [10]
  • More energy.
  • Less bloating and easier passage of gas. [11]
  • And an improvement in overall digestive health.
But here’s the thing… The doctors performing these studies didn’t boost gut diversity to superhuman levels… 

They actually balanced patients’ GMs... 

Restoring them to their original levels. Because in recent times, our guts have come under direct assault…  

From diets high in processed foods and sugar… 

Meat and dairy products full of hormones… 

And in particular… From the western way of treating disease. 
The Drug-Free Path to Your Healthiest Ever Gut
When you hear the words "endangered species," you probably think of big exotic creatures like elephants, leopards and polar bears…

But there's another type of extinction that’s occurring inside your own body.

Inside your GM.

And it’s directly responsible for the rapid rise in imbalances in the gut that create a pathway to sub-optimal health here in the West.

"Over time we are losing valuable members of our community."
- Stanford University
Your GM can range in size from anywhere between 10 to 100 trillion bacteria and other microorganisms. [12] 

Together, they form a delicate environment that must remain balanced if it’s to work. 

Antibiotics disrupt that balance... and can kill both “good” and “bad” bacteria without discretion.  

When researchers at Stanford screened more than 900,000 genetic samples from the stool of healthy men and women who took the antibiotic ciprofloxacin…  

They found bacteria had still not recovered six months later. [13] 

This cull of your body’s resources increases the potential to create a pathway of poor health… 

And in some cases, the GM never fully recovers.
From the year 2000 to 2015, the number of antibiotics in use worldwide increased 39%. [14]

But rather support a healthy gut and immune system that will defend against outside microbial invaders that lead to poor health… 
This increase caused new super resilient bacteria to form. 

And now a growing list of serious infections in the U.S., including:
  •  Pneumonia
  • ​Tuberculosis
  • ​Skin infections
  • ​Blood poisoning
  • ​Gonorrhea
  • ​And several food borne illnesses.
Are becoming more difficult and sometimes even impossible to treat.
Here in the U.S., 30% of oral antibiotics prescribed are unnecessary. [15]
A joint University of California and prestigious Boston Ivy League university study found… 
“Early antibiotic intervention reduces host protective immunity to subsequent infection.”  [16]
In other words…
Taking antibiotics as soon as you feel sick doesn’t allow your immune system to do its job.


Makes viruses stronger.  

To support staying healthy and allowing the bodies defensive system to grow strong, nature has to be allowed to take its course. 

You have to give your immune system a chance to do its job. 
Grow Your Gut’s Defenses and Become Master Of Your Own Body
From the second you’re born, your gut begins to diversify and take in new bacterial residents. [17]

This collection of individuals must work together and live in harmony if they are to thrive. 

When they do, you feel healthy and energetic. 

When they don’t, you share their pain and discomfort. 

A significant drop in one kind of bacteria or a significant rise in another can produce excess gas and chemicals which upset your GM and lead to intestinal discomfort. 

This disruption of your gut’s bacteria is called “dysbiosis.” 
And common signs include:
  • Bad breath
  • Upset stomach
  • Nausea
  • And constipation.
Dysbiosis is the main reason people experience bloating, cramps and abdominal. [18] 

And pain and it can lead to a lifetime of doctor’s visits.

But maintaining a balanced GM needn’t be difficult.
Many people take probiotics to repopulate their guts and maintain balance. Probiotics are live bacteria that can help restore the gut to a healthy state after dysbiosis.

They do this by "reseeding" it with healthy microbes.  [19]

Probiotics can help seal gaps between intestinal cells and support the "leak proof" wall of the intestines.  [20, 21]
Leaky gut occurs when the intestinal wall is damaged. This damage changes the wall’s thickness and can create gaping holes. These holes make many foods indigestible, restricting what you can eat 
Avoid the Supermarket Trap
Now, I really want to stress this…

Probiotics aren’t the yogurt drinks you see sitting on the shelves in supermarkets… 

They have to stimulate the growth of your GM. 

Most supermarket probiotics don’t even come close. 

In fact, when a team of scientists at the University of Copenhagen published a review of seven randomized, placebo-controlled trials… 

(The most scientifically rigorous studies researchers know how to conduct.) 

They found only one study— of just 34 healthy volunteers — showed any significant change. [22] 

If that weren’t cause for concern… 

A Canadian study tested a range of commercial probiotics and found…
Only 27% have a label which properly describes the contents. [23]
When people consume commercial probiotics, they’re hoping the bacteria are the kind their unique gut needs.

But you can never know what kind or how much are in a serving. 

Manufacturers don’t include it on their labels and if you ask, they won’t tell you. The only thing that matters to the food corporations is their bottom line.  

So it’s almost guaranteed you’re getting a tiny dose, too small to make any difference. On top of that, if probiotics are going to be effective they need to be nurtured. 
And it’s important to understand their life cycle has four stages:
1. The Lag phase – When bacteria mature and grow. During this time they adapt to their environment.
2. The Growth phase – When bacteria start replicating. They’re at their WEAKEST during this stage and are vulnerable to damage from their environment.
3. The Static phase – When the bacteria’s growth and death rates level out.
4. And The Death phase – When growth stops and the bacteria start to die off.
Most probiotics arrive at the store in the growth phase...

When they’re most vulnerable to environmental harm.
Taking them at this stage is pointless because they’re almost guaranteed to fail. 

Plus, sitting on a shelf doesn’t do them any good either the microbes reach the death phase quicker and you’re left with a plain old yogurt drink. 

It might be tasty, but it’s not going to do a thing for your gut. 

Overcoming this challenge isn’t a priority for manufacturers though because it’s an industry-wide problem. 

And as long as the competition is in the same boat, No one’s going to rock it. 

No one’s going to rock it.

Typically, commercial probiotics contain a large amount of sugar too. 
If not sugar, then a manufactured sweetener.

Researchers at the University of Georgia found these sweeteners cause gastrointestinal issues. [24]
The same issues people are trying to alleviate by consuming probiotics in the first place! If a probiotic does live long enough to make it to your mouth… 

It then faces an even bigger challenge… Your stomach.

Stomach acid kills the majority of bacteria on contact.

That’s why some commercial probiotics come in capsule form.  The coating helps protect the bacteria from stomach acid long enough to reach your small intestine. 

At least in theory…

Sixty percent of these capsuled probiotic bacteria are still killed prior to reaching the intestine… [25] 

Where they’re supposed to provide their health benefits.  Bacteria are measured in CFUs…

That’s Colony-Forming Units. This number reflects how many bacteria the manufacturer believes can populate your gut. Some products claim to have up to 80 billion…

But it means nothing if more than 99% of those bacteria die before they reach your small intestine.

If a probiotic is boasting more than 20 billion CFUs per dose…

It’s a red flag the manufacturer knows the survival rate is poor. Overloading the CFU count to compensate doesn’t do a thing… 

Except of course, raise the price. 
Beating the Probiotic Problem
In the past, when patients came to me asking me if I could recommend them a probiotic.

I’d tell every one of them the same thing…
“I can’t recommend commercial probiotics, because they don’t reach your lower colon—where they’re needed. Heck, most won’t even survive your stomach.” 
Still, they’d come back asking about some new product on the market and I’d tell them the same thing I told them before. 

I could see no matter what I said, nothing was going to deter them from trying. 
So rather than let this pattern continue…

I decided to tackle the probiotic problem myself. I began by focusing my attention on prebiotics. 

Prebiotics are a special form of fiber that acts as a fertilizer for the good bacteria in your gut. I knew if you could sustain the probiotics on their journey through your colon, provide them with the food and resources to grow, they could survive the hazardous journey and reach their destination. 

Scientists at the University College Cork in Ireland had already proven... 

Probiotic survival rate increased by 99% when combined with prebiotics. [26]

All I needed to do was find the right prebiotics.
The Four Most Robust Prebiotics in Existence
Prebiotic #1: Baobab — The main source of fiber in the Hadza’s Million-Year-Old Diet... 
And the fruit of Africa's “Tree of Life”… 

Baobab contains more antioxidants than any other whole fruit. [27] 

And it is full of:
  • ​Vitamin C
  • ​Potassium
  • ​Calcium
  • ​Magnesium
  • ​Iron
  • Protein.
Baobab fruit has six times more vitamin C than oranges and twice as much calcium as milk.
Baobab is the healthiest banquet your friendly bacteria will ever eat. It's also rich in fiber sustaining your friendly bacteria for a longer period of time 
And helping slow down the release of sugars—the main food source for your “bad” bacteria.

All-in-all, it’s the perfect natural filter for your gut.
Prebiotic #2: Larch Tree Bark—is made up of more than 98% arabinogalactan.
Dutch researchers found arabinogalactan provides more energy for friendly bacteria in your gut than other prebiotics... [28] 

And it also nourishes your gut lining. 

Your gut lining is one of the first lines of defense against harmful substances you might not know you’re eating…
Alpine larch trees in Larch Valley, Lake. Louise, Alberta
So fortifying it means your good bacteria can be better protected while they help foster a stronger environment.
Prebiotic #3: Honeybush — is packed full of different minerals needed for good health:
  • Phosphorus
  • Nitrogen
  • ​Potassium
  • ​Calcium
  • Zinc
  • ​Magnesium
  • Sodium
  • ​Manganese
  • ​Iron
  • and Boron.
Honeybush is exclusive to small regions of South Africa.
This cocktail provides probiotics with a rich source of materials. Improving balance and function in your GM by…
  • Regulating levels of bacteria. 
  • Supporting your immune system.
  • And… even producing extra vitamins.
It’s also an excellent defender… The nutrients in honeybush can prevent the harmful effects of toxins… And reduce their influence on your DNA. [29]
Prebiotic #4: Rooibos — or “Red Bush” has been used as a treatment for occasional diarrhea and stomach issues for centuries. 
It soothes irritation and is antispasmodic...

Meaning it keeps you regular… 

Stems irritation…

And helps prevent imbalances from occurring.
These attributes are essential for probiotics to survive the journey through your colon…  And go on to develop your GM’s natural diversity. Now, when people come to me asking about probiotics and how to defend their guts… 

I make one recommendation… 
The Only Probiotic I’ll Ever Recommend
Primal Biotic is my solution to the probiotic problem.

Containing more than 11 billion survivalist microbes...

It’s able to withstand corrosive stomach acid. and endure the long journey through your colon. 

* Primal Biotic reintroduces your gut to primal flora… 

The same primal flora consumed by our ancestors over thousands of years in our evolution.

Our ancestors got their probiotics from the foods they ate…

From the land brimming with mega doses of good environmental bacteria. 
These are nature’s true probiotics. Reintroducing them to your GM restores a balance that’s been upset since before you were born.
* Primal Biotic includes the most resilient strains known to science. Strains like Bacillus subtilis. Which can survive a six-year journey in space. [30] 

Unaffected by harsh radiation, vacuum, temperatures and other conditions that don’t support life.

Its protective outer shell, known as an endospore, allows it to:
  • Survive different hostile environments. 
  • Successfully pass through the acidic gastric system.
  • ​And thrive once it reaches your GM.
* The flora in Primal Biotic care cultured by microbiologists in a dedicated lab environment expertly tended until they enter their lag phase— 

The exact time they’re at their strongest and most resilient.
There’s no sitting around in a box or cooking on a shelf in the sun. They’re primed and ready to adapt to your gut. 

They work individually when carrying out specific tasks and as part of a team when building up gut defenses. A recent study by researchers in Finland found when different strains are combined, powerful partnerships are formed… 

Partnerships that build a more sustainable environment in your gut. [31] 

The variety of strains also provides further balance, meaning no one strain has the chance to become too dominant.

In all, I included 11 different strains for maximum diversity.

And I boosted their collective power by partnering them with the 4 most robust prebioticsin existence: Baobab, Larch tree bark, Honeybush and Rooibos.
One Capsule Supports Superior Digestive 
Now, for the first time, there’s a probiotic formula that does exactly what you need it to.

A primal formula filled with nutrients readily available to your ancestors. 

Nutrients that feed the primal flora proven to support a healthy GM and… 
  • Help boost your immune system 
  • Improve your mood
  • Charge your energy levels
  • Promote the loss of weight and belly fat
  • And support the health of your intestinal lining offering a great defense for your entire body
No more medicine cabinets overflowing with pills. This one capsule gives you complete control. I’ve tailored it specifically to my patients’ needs.

And now I want to make sure everyone has access to it. That’s why I’m dropping the price as low as I can…

And even taking care of shipping costs because I know this will be a game changer for you.

I’m also including a FREE bottle for everyone who orders now…

So supplies can last you even longer.  This is your personal “Best Deal” offer… 
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Yet that’s not all…

You’ll also receive 3 FREE Special e-Reports... 
FREE e-Report No.1: New Secrets to Great Gut Health

Normally $19.95, it’s yours FREE when you order my “Best Deal” package.
In this valuable special e-Report, you’ll learn:
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Primal Biotic Is Relief in a Bottle
The unique primal probiotics and prebioticsin my new Primal Biotic have made are markable difference in my patients’ lives. Giving them a new lease on life and complete peace of mind…

And now, you can take the exact same nutrients... without risk. In fact, for any reason — or for no reason at all — if you do not want to continue taking Primal Biotic…
Just return the unused portion or even empty bottles within 90 days of purchase.

You’ll promptly receive a FREE REFUND of every penny paid.

And whatever you decide, any bonus gifts are yours to keep.

So act now.

Put an END to your worries now and forever…

With the power of the primal probiotics and prebiotics…

My patients have been enjoying great results:

“I have zero problems with my gut.” – Belinda M.

“My energy has come back from nowhere.” - Kathy D.

“I feel fit, focused and happy.” – Winter S.
Now, they’re back to enjoying their lives…

And now, for the first time, you too can take these same gut-restoring nutrients in my new Primal Biotic.

You have absolutely nothing to lose and great digestive, elimination and GI health to gain…
So order the new Primal Biotic today.

To Your Good Health,
Al Sears, MD, CNS
P.S. I urge you to hurry and order now. I expect once word gets out about this new gut-restoring formula, we’ll be slammed with orders — and I don’t want to run out. If so, that will mean ordering more, and you’ll likely have to wait weeks for your supply. So get your bottles of Primal Biotic now, when you can. Order today. 

P.P.S. Don’t forget. Your “Best Deal” of Primal Biotic includes a FREE bottle (a 1-month supply value that $49.95) and the lowest price per bottle and greatest savings... plus three FREE Gifts,  FREE Shipping and a Money-Back Guarantee.

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Here’s what industry experts are saying about Dr. Sears:
“Dr. Sears blows away the conventional medical wisdom…”
-Ronald Klatz, MD, DO Founder and President, American Academy of Anti-Aging Medicine

“Dr. Sears has distinguished himself as a leader in the area of Anti-Aging Medicine and recently in cell and telomere biology…”
-Frederic J. Vagnini, MD, FACS;
Medical Director of the Heart, Diabetes and Weight Loss Centers of NY

“Dr. Sears masterfully explains how we can flip the switches that allow access to the store of human vitality that resides within each one of us. We understood how to do this when we were young and now Dr. Sears gives us the evidence-based means to tap into our potency, strength, and stamina with intention.”
-Paul L. Hester, MD, MBA

“Dr. Al Sears really gets it. What a refreshing breath of fresh air…”
-Jonny Bowden, author, Living the Low Carb Life: From Atkins to the Zone Choosing the Diet That’s Right for You
1. Smits SA, et al. “Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania.” Science. 2017;357(6353):802-806.

2. Vighi G, et al. “Allergy and the gastrointestinal system.” Clin Exp Immunol. 2008;153(Suppl 1):3-6. 

3. Bonaz B, et al. “The vagus nerve in the neuro-immune axis: Implications in the pathology of the gastrointestinal tract.” Front Immunol. 2017;8:1452. 

4. Quigley EM. “Gut bacteria in health and disease.” Gastroenterol Hepatol (N Y). 2013;9(9):560-569.

5. Ursell LK, et al. “Defining the human microbiome.” Nutr Rev. 2012;70(Suppl 1):S38-S44. 

6. Schnorr SL, et al. “Gut microbiome of the Hadza hunter-gatherers.” Nat Commun. 2014;5:3654.

7.Spector, T. I spent three days as a hunter-gatherer to see if it would improve my gut health. [online] The Conversation. (2019). Available at: [Accessed 8 Feb. 2019].

8. Sazawal S, et al. “Efficacy of probiotics in prevention of acute diarrhea: A meta-analysis of masked, randomized, placebo-controlled trials.” Lancet Infect Dis. 2006;6(6):374-382.

9. Enck P, et al. “Randomized controlled treatment trial of irritable bowel syndrome with a probiotic E.-coli preparation (DSM17252) compared to placebo.” Z Gastroenterol. 2009;47(2):209-214.

10. Visser MJE, et al. “Bacterial dysbiosis and translocation in psoriasis vulgaris.” Front Cell Infect Microbiol. 2019;9:7. 

11.Whorwell PJ, et al. “Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome.” Am J Gastroenterol. 2006;101(7):1581-1590.
12. Sender R, et al. “Revised estimates for the number of human and bacteria cells in the body.” PLoS Biol. 2016;14(8):e1002533. 

13. Dethlefsen L, et al. “The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing.” PLoS Biol. 2008;6(11):e280.

14. Klein EY, et al. “Global increase and geographic convergence in antibiotic consumption between 2000 and 2015.” Proc Natl Acad Sci U S A. 2018;115(15):E3463-E3470. 

15. Centers for Disease Control and Prevention, Outpatient Antibiotic Prescriptions—United States, 2014, accessed Dec. 12, 2016,

16. Benoun J, et al. “Collateral damage: Detrimental effect of antibiotics on the development of protective immune memory.” mBio. 2016;7(6):e01520-16.

17. Hill CJ, et al. “Evolution of gut microbiota composition from birth to 24 weeks in the INFANTMET Cohort.” Microbiome. 2017;5(1):4. 

18. Pozuelo M, et al. “Reduction of butyrate- and methane-producing microorganisms in patients with Irritable Bowel Syndrome.” Sci Rep. 2015;5:12693. 

19. McFarland LV. “Use of probiotics to correct dysbiosis of normal microbiota following disease or disruptive events: A systematic review.” BMJ Open. 2014;4(8):e005047. 

20. Rao RK and Samak G. “Protection and restitution of gut barrier by probiotics: Nutritional and clinical implications. Curr Nutr Food Sci. 2013;9(2):99-107. 

21. Bischoff SC, et al. “Intestinal permeability--a new target for disease prevention and therapy.” BMC Gastroenterol. 2014;14:189.

22.  Kristensen NB, et al. “Alterations in fecal microbiota composition by probiotic supplementation in healthy adults: A systematic review of randomized controlled trials.” Genome Med. 2016;8(1):52.

23. Weese JS and Martin H. “Assessment of commercial probiotic bacterial contents and label accuracy.” Can Vet J. 2011;52(1):43-46.

24. Bian X, et al. “Gut microbiome response to sucralose and its potential role in inducing liver inflammation in mice.” Front Physiol. 2017;8:487.

25. Govender M, et al. “A review of the advancements in probiotic delivery: Conventional vs. non-conventional formulations for intestinal flora supplementation.” AAPS PharmSciTech. 2013;15(1):29-43.

26. Corcoran BM, et al. “Survival of probiotic lactobacilli in acidic environments is enhanced in the presence of metabolizable sugars.” Appl Environ Microbiol. 2005;71(6):3060-3067.

27. Braca A, et al. “Phytochemical profile, antioxidant and antidiabetic activities of adansonia digitata L. (baobab) from Mali, as a source of health-promoting compounds.” Molecules. 2018;23(12):3104.

28. Aguirre M., et al. “The gut microbiota from lean and obese subjects contribute differently to the fermentation of arabinogalactan and inulin.” PLoS One. 2016;11(7):e0159236.

29. Sharmanov TSh, et al. “[Effect of the type of nutrition and aflatoxin B1 on the structure of the chromosomes]”. Vopr Pitan. 1986;5:56-60.

30. Horneck G, et al. “Resistance of bacterial endospores to outer space for planetary protection purposes--experiment PROTECT of the EXPOSE-E mission.” Astrobiology. 2012;12(5):445-456.

31. Ouwehand AC, et al. “The mucus binding of Bifidobacterium lactis Bb12 is enhanced in the presence of Lactobacillus GG and Lact. delbrueckii subsp. bulgaricus.” Lett Appl Microbiol. 2000;30(1):10-13.
These statements have not been evaluated by the U.S. Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease. 
One bottle of RECOVERY: Metabolic Rescue at the regular price of $49.95, plus $8.95 for shipping.
* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
1. Wijngaarden MA, et al. “Effects of prolonged fasting on AMPK signaling, gene expression, and mitochondrial respiratory chain content in skeletal muscle from lean and obese individuals.” Am J Physiol. 2013;304(9): E1012-E1021.

2. Hardie DG, et al. “AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs.” Trends Cell Biol. 2016; 26(3):190-201.

3. Hu R, et al. “Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase.” Sci Rep. 2017;7(1):778.

4. Salk scientists uncover the health effects of metabolic “magic bullet” protein. Salk News. January 14, 2019. Available here: 

5. Ibid. 

6. Cao J, et al. “Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK).” J Biol Chem. 2014;289: 20435-20446. 

7. McCrimmon RJ, et al. “Potential role for AMP-activated protein kinase in hypoglycemia sensing in the ventromedial hypothalamus.” Diabetes. 2004;53(8):1953-1958. 

8. Coughlan KA, et al. “AMPK activation: A therapeutic target for type 2 diabetes?” Diabetes Metab Syndr Obes. 2014;7:241-253. 

9. Adachi Y, et al. “l-Alanine activates hepatic AMP-activated protein kinase and modulates systemic glucose metabolism.” Mol Metab. 2018;17:61-70. 

10. Soloman TP and Blannin AK. “Effects of short-term cinnamon ingestion on in vivo glucose tolerance.” Diabetes Obes Metab. 2007;9(6):895-901. 

11. Mollazadeh H and Hosseinzadeh H. “Cinnamon effects on metabolic syndrome: a review based on its mechanisms.” Iran J Basic Med Sci. 2016;19(12):1258-1270. 

12. USDA. “Insulin imitators: Polyphenols found in cinnamon mimic job of hormone.” Accessed on March 25, 2019. 

13. Khan A, et al. “Cinnamon improves glucose and lipids of people with type 2 diabetes.” Diabetes Care. 2003;26(12):3215-3218. 

14. Jarvill-Taylor KJ, et al. “A hydroxychalcone derived from cinnamon functions as a mimetic for insulin in 3T3-L1 adipocytes.” J Am Coll Nutri. 2001;20(4):327-336. 

15. Healthline. Insulin and Insulin Resistance - The Ultimate Guide. Updated August 30, 2015 Accessed April 19, 2019. 

16. Allen RW, et al. “Cinnamon use in type 2 diabetes: An updated systematic review and meta-analysis.” Ann Fam Med. 2013;11(5):452-459. 

17. Crawford P. “Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: A randomized, controlled trial.” J Am Board Fam Med. 2009;22(5):507-512. 

18. Hlebowitz J, et al. “Effect of cinnamon on postprandial blood glucose, gastric emptying, and satiety in healthy subjects.” Am J Clin Nutr. 2007;86(6):1552-1556.  

19. Ibid. 

20. Ranasinghe P, et al. “Medicinal properties of ‘true’ cinnamon (Cinnamomum zeylanicum): A systematic review.” BMC Complement Altern Med. 2013;13:275. 

21. Benhaddou-Andaloussi A, et al. “The in vivo antidiabetic activity of Nigella sativa is mediated through activation of the AMPK pathway and increased muscle Glut4 content.” Evid Based Comp Alt Med. 2011;2011:538671. 

22. Kanter M, et al. “Partial regeneration/proliferation of the beta-cells in the islets of Langerhans by Nigella sativa L. in streptozotocin-induced diabetic rats.” Tohoku J Exp Med. 2003;201(4): 213-219.  

23. Bamosa AO, et al. “Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus.” Indian J Physiol Pharmacol. 2010;54(4):344-354. 

24. Tan MJ, et al. “Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway.” Chem Biol. 2008;15(3):263-273. 

25. Leung L, et al. “Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): A mini review.” Br J Nutr. 2009;102(12):1703-1708. 

26. Kong WJ, et al. “Berberine reduces insulin resistance through protein kinase C-dependent up-regulation of insulin receptor expression.” Metabolism. 2009;58(1):109-119. 

27. Yin J, et al. “Efficacy of berberine in patients with type 2 diabetes.” Metabolism. 2008;57(5):712-717.

28. Hu Y, et al. “Lipid-lowering effect of berberine in human subjects and rats.” Phytomedicine. 2012;19(10):861-867. 

29. Yin J, et al. “Effects and mechanisms of berberine in diabetes treatment.” Acta Pharm Sin B. 2012;2(4):327-334. 

30. Dong H, et al. “The effects of berberine on blood lipids: A systemic review and meta-analysis of randomized controlled trials.” Planta Med. 2013;79(6):437-446. 

31. Brala PM and Hagen RL. “Effects of sweetness perception and caloric value of a preload on short term intake.” Physiol Behav. 1983;30(1):1-9. 

32. Diabetes In Control Newsletter. Effect of extended release gymnema sylvestre leaf extract (beta fast GXR). Updated January 6, 2011. Accessed April 23, 2019. 

33. Pothuraju R, et al. “A systematic review of Gymnema sylvestre in obesity and diabetes management.” J Sci Food Agric. 2014;94(5):834-840. 

34. Preuss HG, et al. “Effects of a natural extract of (-)-hydroxycitric acid (HCA-SX) and a combination of HCA-SX plus niacin-bound chromium and Gymnema sylvestre extract on weight loss.” Diabetes Obes Metab. 2004;6(3):171-180. 

35. Anderson R, et al. “Elevated intakes of supplemental chromium improve glucose and insulin variables in individuals with type 2 diabetes.” Diabetes. 1997;46:1786-1791. 

36. Simental-Mendia LE, et al. “A systematic review and meta-analysis of randomized controlled trials on the effects of magnesium supplementation on insulin sensitivity and glucose control.” Pharmacol Res. 2016;111:272-282. 

37. Chuengsamarn S, et al. “Curcumin extract for prevention of type 2 diabetes.” Diabetes Care. 2012;35(11): 2121-2127. 

38. Abenavoli L, et al. “Milk thistle in liver diseases: Past, present, future.” Phytother Res. 2010;24(10):1423-1432. 

39. Science Daily. Lipoic Acid Explored As Anti-aging Compound. Updated May 18, 2007. Accessed April 23, 2019.